Article

Immunogenetics of Gastrointestinal Cancers: A Systematic Review of Inborn Errors of Immunity in Humans

2022-01-25

Abstract excerpt

<h4>Background/Aims</h4> The immune system plays a key role in cancer surveillance and modulation of the tumor microenvironment. Humans with inborn errors of immunity (IEI), or primary immunodeficiencies, may be prone to recurrent mucosal bacterial and viral infections and chronic inflammation, associated with intrinsic or secondary epithelium dysfunction, a potential risk factor for early-onset gastrointestinal...

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Literature Corpus work: f733c871-2fd3-5a65-bba5-db5e5739ae02
DOI: 10.1101/2022.01.25.22269823

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