Article

Clinical presentation, karyotypic characterization, and treatment outcome of childhood acute lymphoblastic leukemia with a near-haploid or hypodiploid less than 45 line

1990-03-01

Abstract excerpt

Abstract Cytogenetic and DNA flow cytometric analyses of leukemic cells from 2,184 children with newly diagnosed acute lymphoblastic leukemia (ALL) identified 27 cases (1.2%) that had a hypodiploid line with fewer than 45 chromosomes per cell. Had cytogenetic techniques been used alone, seven cases would have been missed, compared with five if only flow cytometry had been used. For comparative purposes, the 27 cas...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: f72418cc-62c1-578a-9a53-08a5fb522ec7
DOI: 10.1182/blood.v75.5.1170.1170

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Clinical presentation, karyotypic characterization, and treatment outcome of childhood acute lymphoblastic leukemia with a near-haploid or hypodiploid less than 45 lineDOI 10.1182/blood.v75.5.1170.1170Read

Clinical presentation, karyotypic characterization, and treatment outcome of childhood acute lymphoblastic leukemia with a near-haploid or hypodiploid less than 45 lineSemantic proximity Read

Hypodiploidy with less than 45 chromosomes confers adverse risk in childhood acute lymphoblastic leukemia: a report from the children's cancer group.Semantic proximity Read

Near-haploid and low-hypodiploid acute lymphoblastic leukemia: two distinct subtypes with consistently poor prognosis.Semantic proximity Read

Three distinct subgroups of hypodiploidy in acute lymphoblastic leukaemiaSemantic proximity Read

Near-Haploidy and Low-Hypodiploidy in B-Cell Acute Lymphoblastic Leukemia: When Less Is Too MuchSemantic proximity Read

Near-triploid and near-tetraploid acute lymphoblastic leukemia of childhood.Semantic proximity Read

Outcome of treatment in children with hypodiploid acute lymphoblastic leukemiaSemantic proximity Read

Reassessment of the prognostic significance of hypodiploidy in pediatric patients with acute lymphoblastic leukemiaSemantic proximity Read

High hyperdiploid childhood acute lymphoblastic leukemiaSemantic proximity Read

Genetic and epigenetic characterization of hypodiploid acute lymphoblastic leukemia.Semantic proximity Read

The genomic landscape of hypodiploid acute lymphoblastic leukemia.Semantic proximity Read

Hyperdiploid Acute Lymphoblastic Leukemia With 51 to 65 Chromosomes: A Distinct Biological Entity With a Marked Propensity to Undergo ApoptosisSemantic proximity Read