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Transcriptional Analysis of Coccidioides immitis Mycelia and Spherules by RNA Sequencing

7 May 2021

Abstract excerpt

Coccidioides immitis and C. posadasii are dimorphic fungi that transform from mycelia with internal arthroconidia in the soil to a tissue form known as a spherule in mammals. This process can be recapitulated in vitro by increasing the temperature, CO2 and changing other culture conditions. In this study, we have analyzed changes in gene expression in mycelia and young and mature spherules. Genes that were highly...

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PMID: 34067070
DOI: 10.3390/jof7050366

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