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Adipogenic MSC-derived COL-3 Drives M2 Macrophage Polarization via PI3K-AKT to Alleviate Sepsis-induced Lung Injury

2026-02-10

Abstract excerpt

<title>Abstract</title> <p>Sepsis-induced acute lung injury is a critical condition marked by uncontrolled inflammation and immune imbalance. Here, we investigated the role of extracellular matrix components derived from adipogenically differentiated adipose-derived stem cells in regulating macrophage polarization and lung injury. We found that type III collagen was significantly upregulated in the extracellular...

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Literature Corpus work
f6d486bc-4944-5991-a5b0-d295feccd11b
DOI
10.21203/rs.3.rs-8375617/v1
Open publication

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Adipogenic MSC-derived COL-3 Drives M2 Macrophage Polarization via PI3K-AKT to Alleviate Sepsis-induced Lung InjuryDOI 10.21203/rs.3.rs-8375617/v1
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