Article

Alcohol Use Disorder Causes Profound Global Changes in Gene Expression and Splicing in the Liver

2025-05-08

Abstract excerpt

<title>Abstract</title> <p>Objective Alcohol use disorder (AUD) is a widespread illness commonly leading to alcoholic liver disease (ALD) and cirrhosis with an increased incidence of hepatocellular carcinoma (HCC), but the mechanisms of alcohol-related oncogenesis in the liver are incompletely understood. Splicing represents a mechanism of messenger RNA processing, and its impairment is implicated in various can...

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Literature Corpus work: f6962784-5474-5240-a1e1-3391c4c5d31a
DOI: 10.21203/rs.3.rs-6507570/v1

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