Article

CG-rich trinucleotide two-repeats may be the long-sought recombination hotspot loci shared across primates and mouse

2023-11-30

Abstract excerpt

CG-rich trinucleotide short tandem repeats (STRs) are linked with human cognition and various neurodevelopmental, neurological, and movement disorders. However, the fundamental two-repeat units of these STRs remain unexplored. On a genome-wide scale, here we mapped the two-repeat units of all combinations of CG-rich trinucleotides in human. We found 81,118 colonies (distance between each unit <500 bp). Subsequentl...

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Literature Corpus work: f5e3de16-b1ff-59c3-8acc-45db1a3265d1
DOI: 10.21203/rs.3.rs-3666512/v1

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