Article

β-Nicotinamide mononucleotide: a novel broad-spectrum CRISPR inhibitor

2025-11-26

Abstract excerpt

CRISPR–Cas systems have revolutionized genome editing with their precision and versatility, enabling transformative applications in various fields, especially in the treatment of genetic diseases. However, the clinical translation of this technology is hindered by challenges such as off-target effects and uncontrolled nuclease activity. At the same time, it has the possibility of causing biosecurity risks, undersc...

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Literature Corpus work: f5b69608-0ea3-580f-b15d-d64ffdf477cc
DOI: 10.1101/2025.11.22.685598

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