Back to search

Article

Genetic heterogeneity of the Spy1336/R28 – Spy1337 Virulence Axis in <i>Streptococcus pyogenes</i> and Effect on Gene Transcript Levels and Pathogenesis

2019-09-23

Abstract excerpt

<h4>ABSTRACT</h4> Streptococcus pyogenes is a strict human pathogen responsible for more than 700 million infections annually worldwide. Strains of serotype M28 S. pyogenes are typically among the five more abundant types causing invasive infections and pharyngitis in adults and children. Type M28 strains also have an unusual propensity to cause puerperal sepsis and neonatal disease. We recently discovered that...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
f5456375-714e-5033-a758-e1df95b5044c
DOI
10.1101/777987
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Genetic heterogeneity of the Spy1336/R28 – Spy1337 Virulence Axis in <i>Streptococcus pyogenes</i> and Effect on Gene Transcript Levels and PathogenesisDOI 10.1101/777987
Identifying Genetic Variations in <i>emm</i> 89 <i>Streptococcus pyogenes</i> Associated with Severe Invasive InfectionsSemantic proximity
Transcriptome remodeling contributes to epidemic disease caused by the human pathogen <i>Streptococcus pyogenes</i>Semantic proximity
A genome-wide association study of emm89 Streptococcus pyogenes identifies genetic variations contributing to severe invasive infectionsSemantic proximity
Transcriptome Remodeling Contributes to Epidemic Disease Caused by the Human Pathogen Streptococcus pyogenes.Semantic proximity
Insights into <i>Streptococcus Pyogenes</i> Pathogenesis from Transcriptome StudiesSemantic proximity
Conserved and specific features of Streptococcus pyogenes and Streptococcus agalactiae transcriptional landscapesSemantic proximity
Cryptic prophages within a <i>Streptococcus pyogenes</i> genotype <i>emm</i> 4 lineageSemantic proximity
Intergenic Variable-Number Tandem-Repeat Polymorphism Upstream of rocA Alters Toxin Production and Enhances Virulence in Streptococcus pyogenes.Semantic proximity
Naturally occurring single amino acid replacements in a regulatory protein alter streptococcal gene expression and virulence in mice.Semantic proximity
Cryptic prophages within a Streptococcus pyogenes genotype emm4 lineage.Semantic proximity
Genome Sequence of a Serotype M28 Strain of Group A<i>Streptococcus:</i>Potential New Insights into Puerperal Sepsis and Bacterial Disease SpecificitySemantic proximity
The Bacteriophages of<i>Streptococcus pyogenes</i>Semantic proximity
Select a neighboring publication to make it the new centre.