Genome Sequence of a Serotype M28 Strain of Group A<i>Streptococcus:</i>Potential New Insights into Puerperal Sepsis and Bacterial Disease Specificity

Abstract excerpt

Puerperal sepsis, a major cause of death of young women in Europe in the 1800s, was due predominantly to the gram-positive pathogen group A Streptococcus. Studies conducted during past decades have shown that serotype M28 strains are the major group A Streptococcus organisms responsible for many of these infections. To begin to increase our understanding of their enrichment in puerperal sepsis, we sequenced the...