Article

Targeting ARF4-mediated intracellular transport as broad-spectrum antivirals

2024-03-11

Abstract excerpt

<title>Abstract</title> <p>Host factors that regulate cellular vesicular trafficking also contribute to progeny virions’ destination, thus representing as potential antiviral drug targets. Here we demonstrate that genetic deletion of ARF4, a regulator in vesicle transport, repressed multiple pathogenic RNA viral infections including Zika virus (ZIKV), influenza A virus (IAV), SARS-CoV-2 and Vesicular Stomatitis v...

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Literature Corpus work: f532ebb8-37d3-57e1-9591-13c3ff8d35a6
DOI: 10.21203/rs.3.rs-4017169/v1

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