Article
Altered global gene expression in first trimester placentas of women destined to develop preeclampsia.
Placenta - 1 Jan 2009
Founds S A, Conley Y P, Lyons-Weiler J F, Jeyabalan A, Hogge W Allen, Conrad K P
Abstract excerpt
BACKGROUND: Preeclampsia is a pregnancy-specific disorder that remains a leading cause of maternal, fetal and neonatal morbidity and mortality, and is associated with risk for future cardiovascular disease. There are no reliable predictors, specific preventative measures or treatments other than delivery. A widely held view is that the antecedents of preeclampsia lie with impaired placentation in early pregnancy....
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