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Article

Interaction between the SifA virulence factor and its host target SKIP is essential for Salmonella pathogenesis.

The Journal of biological chemistry - 27 Nov 2009

Diacovich Lautaro, Dumont Audrey, Lafitte Daniel, Soprano Elodie, Guilhon Aude-Agnès, Bignon Christophe, Gorvel Jean-Pierre, Bourne Yves, Méresse Stéphane

Abstract excerpt

SifA is a Salmonella effector that is translocated into infected cells by the pathogenicity island 2-encoded type 3 secretion system. SifA is a critical virulence factor. Previous studies demonstrated that, upon translocation, SifA binds the pleckstrin homology motif of the eukaryotic host protei...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 19801640
DOI: 10.1074/jbc.M109.034975
PMCID: PMC2785157

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19801640-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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