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Article

The EAL-like protein STM1697 regulates virulence phenotypes, motility and biofilm formation in Salmonella typhimurium.

Molecular microbiology - 1 Dec 2013

Ahmad Irfan, Wigren Edvard, Le Guyon Soazig, Vekkeli Santtu, Blanka Andrea, El Mouali Youssef, Anwar Naeem, Chuah Mary Lay, Lünsdorf Heinrich, Frank Ronald, Rhen Mikael, Liang Zhao-Xun, Lindqvist Ylva, Römling Ute

Abstract excerpt

The ubiquitous second messenger c-di-GMP regulates the switching of bacterial lifestyles from motility to sessility and acute to chronic virulence to adjust bacterial fitness to altered environmental conditions. Conventionally, EAL proteins being c-di-GMP phosphodiesterases promote motility and acute virulence phenotypes such as invasion into epithelial cells and inhibit biofilm formation. We report here that in...

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PMID: 24127899
DOI: 10.1111/mmi.12428

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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