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Cytomegalovirus pentamer dependent endocytic cellular infection utilizes redundant entry receptors in the guinea pig model

2026-05-08

Abstract excerpt

2. The guinea pig with guinea pig cytomegalovirus (GPCMV) is the only small animal model for congenital CMV (cCMV). GPCMV cell entry is dictated by specific viral gH/gL-based complexes: gH/gL/gO trimer (direct entry); pentamer complex, PC (endocytic entry). GPCMV gB as the fusogenic protein is also essential for all entry pathways. PDGFRA and NRP2 are receptors for direct and endocytic virus entry respectively bas...

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Literature Corpus work
f47ba36a-9505-586d-ac8e-09ed83da7ad6
DOI
10.64898/2026.05.07.723586
Open publication

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Cytomegalovirus pentamer dependent endocytic cellular infection utilizes redundant entry receptors in the guinea pig modelDOI 10.64898/2026.05.07.723586
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