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Article

Requirements for guinea pig cytomegalovirus tropism and antibody neutralization on placental amniotic sac cells.

The Journal of general virology - 1 Apr 2020

Choi K Yeon, El-Hamdi Nadia S, McGregor Alistair

Abstract excerpt

Congenital cytomegalovirus (cCMV) is a leading cause of birth defects. The guinea pig is the only small cCMV animal model. Guinea pig cytomegalovirus (GPCMV) encodes similar glycoprotein complexes to human CMV (HCMV) including gB and the gH-based pentamer complex (PC). In HCMV, both gB and PC are neutralizing antibody antigens. The relevance of GPCMV PC for virus tropism and vaccine target remains controversial....

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Identifiers

PMID: 32068527
DOI: 10.1099/jgv.0.001394
PMCID: PMC7414438

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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