Article

Validation and Implementation of CLIA-Compliant Whole Genome Sequencing (WGS) in Public Health Laboratory

2017-02-08

Abstract excerpt

<h4>Background</h4> Public health microbiology laboratories (PHL) are at the cusp of unprecedented improvements in pathogen identification, antibiotic resistance detection, and outbreak investigation by using whole genome sequencing (WGS). However, considerable challenges remain due to the lack of common standards. <h4>Objectives</h4> 1) Establish the performance specifications of WGS applications used in PHL to...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: b0c43847-0535-51a6-97a4-39a8c265d2e8
DOI: 10.1101/107003

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Validation and Implementation of CLIA-Compliant Whole Genome Sequencing (WGS) in Public Health LaboratoryDOI 10.1101/107003Read

Validation and Implementation of Clinical Laboratory Improvements Act-Compliant Whole-Genome Sequencing in the Public Health Microbiology LaboratorySemantic proximity Read

Proficiency Testing for bacterial whole genome sequencing in assuring the quality of microbiology diagnostics in clinical and public health laboratoriesSemantic proximity Read

Whole genome sequencing in clinical and public health microbiologySemantic proximity Read

Bacterial genome sequencing in clinical microbiology: a pathogen-oriented reviewSemantic proximity Read

Validation, Implementation, and Clinical Utility of Whole Genome Sequence-Based Bacterial Identification in the Clinical Microbiology LaboratorySemantic proximity Read

Next Generation and Other Sequencing Technologies in Diagnostic Microbiology and Infectious DiseasesSemantic proximity Read

Survey on the Use of Whole-Genome Sequencing for Infectious Diseases Surveillance: Rapid Expansion of European National Capacities, 2015–2016Semantic proximity Read

A Bioinformatics Whole-Genome Sequencing Workflow for Clinical Mycobacterium tuberculosis Complex Isolate Analysis, Validated Using a Reference Collection Extensively Characterized with Conventional Methods and In Silico Approaches.Semantic proximity Read

Clinical implementation of routine whole-genome sequencing for hospital infection control of multi-drug resistant pathogensSemantic proximity Read

RSYD-BASIC: a bioinformatics pipeline for Routine Sequence analYsis and Data processing of BActerial iSolates for clInical miCrobiologySemantic proximity Read

Improving the quality and workflow of bacterial genome sequencing and analysis: paving the way for a Switzerland-wide molecular epidemiological surveillance platformSemantic proximity Read

From Theory to Practice: Translating Whole-Genome Sequencing (WGS) into the Clinic.Semantic proximity Read