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Article

Rapid whole genome characterization of antimicrobial-resistant pathogens using long-read sequencing to identify potential healthcare transmission.

Infection control and hospital epidemiology - 1 Feb 2025

Wu Chin-Ting, Shropshire William C, Bhatti Micah M, Cantu Sherry, Glover Israel K, Anand Selvalakshmi Selvaraj, Liu Xiaojun, Kalia Awdhesh, Treangen Todd J, Chemaly Roy F, Spallone Amy, Shelburne Samuel

Abstract excerpt

OBJECTIVE: Whole genome sequencing (WGS) can help identify transmission of pathogens causing healthcare-associated infections (HAIs). However, the current gold standard of short-read, Illumina-based WGS is labor and time intensive. Given recent improvements in long-read Oxford Nanopore Technologies (ONT) sequencing, we sought to establish a low resource approach providing accurate WGS-pathogen comparison within a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39727230
DOI: 10.1017/ice.2024.202
PMCID: PMC11790330

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