Article

Systemic Metabolic Depletion of Intestine Microbiome Undermines Melanoma Immunotherapy Effectiveness

2023-10-11

Abstract excerpt

Immunotherapy has proven to be a boon for patients grappling with metastatic melanoma, significantly enhancing their clinical condition and overall quality of life. A compelling connection was discovered between the composition of the intestinal microbiome and the effectiveness of immunotherapy substantiated in both animal models and human patients. Nonetheless, the precise biological mechanisms through which gut...

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Literature Corpus work: f468abce-541d-52a3-8582-ffc1bad9bc24
DOI: 10.1101/2023.10.09.561540

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