Article

Meta-analytic microbiome target discovery for immune checkpoint inhibitor response in advanced melanoma

2025-03-21

Abstract excerpt

Immune checkpoint inhibitors (ICIs) have revolutionized melanoma treatment, yet patient responses remain highly variable, underscoring the need for predictive biomarkers. Emerging evidence suggests that gut microbiome composition influences ICI efficacy, though findings remain inconsistent across studies. Here, we present a meta-analysis of seven melanoma-associated microbiome cohorts (N=678) using a standardized...

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Literature Corpus work: 7cbe2e33-2ecc-57fc-bcd8-0df941468762
DOI: 10.1101/2025.03.21.644637

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