Article
Systemic metabolic depletion of gut microbiome undermines responsiveness to melanoma immunotherapy
6 Mar 2024
Abstract excerpt
Immunotherapy has proven to be a boon for patients battling metastatic melanoma, significantly improving their clinical condition and overall quality of life. A compelling link between the composition of the gut microbiome and the efficacy of immunotherapy has been established in both animal models and human patients. However, the precise biological mechanisms by which gut microbes influence treatment outcomes...
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