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Gut Microbiota and Therapy in Metastatic Melanoma: Focus on MAPK Pathway Inhibition

9 Oct 2022

Abstract excerpt

Gut microbiome (GM) and its either pro-tumorigenic or anti-tumorigenic role is intriguing and constitutes an evolving landscape in translational oncology. It has been suggested that these microorganisms may be involved in carcinogenesis, cancer treatment response and resistance, as well as predisposition to adverse effects. In melanoma patients, one of the most immunogenic cancers, immune checkpoint inhibitors...

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PMID: 36233289
DOI: 10.3390/ijms231911990

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