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Combining Bioinformatics and Experiments to Identify MAD2L2 as a Key Regulator in Ovarian Cancer

2022-05-31

Abstract excerpt

Ovarian cancer (OVCA) is a common gynecological malignant tumor and the fourth most common female tumor, following breast cancer, cervical cancer and endometrial cancer. Spindle Assembly checkpoint (SAC) can finely control the dynamic balance between kinetosomes and microtubules during mitosis. MAD2L2 is a chromatin binding protein and selective shear body of MAD2, one part of SAC. However, the expression and prog...

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Literature Corpus work
f46299ca-b987-5a34-9afd-98eb6546e1d1
DOI
10.21203/rs.3.rs-1692439/v1
Open publication

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