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MAD2L2, a key regulator in ovarian cancer and promoting tumor progression

2 Jan 2024

Abstract excerpt

Ovarian cancer (OVCA), a prevalent gynecological malignancy, ranks as the fourth most common cancer among women. Mitotic Arrest Deficient 2 Like 2 (MAD2L2), a chromatin-binding protein and a component of DNA polymerase ζ, has been previously identified as an inhibitor of tumor growth in colorectal cancer. However, the roles of MAD2L2 in OVCA, including its expression, impact, and prognostic significance, remain...

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PMID: 38167649
DOI: 10.1038/s41598-023-50744-7

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