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Spindle component 25 predicts the prognosis and the immunotherapy response of cancers: a pan-cancer analysis

11 Apr 2024

Abstract excerpt

Spindle component 25 (SPC25) is one of the four proteins that make up the nuclear division cycle 80 (NDC80) complex, the other three components being Ndc80p, Nuf2p, and spindle component 24. Deregulation of the components of this complex can lead to uncontrolled proliferation and reduced apoptosis. However, the prognostic and immunotherapeutic value of SPC25 in pan-cancer remains unclear. Data from the UCSC Xena,...

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PMID: 38605119
DOI: 10.1038/s41598-024-59038-y

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