Article

Differential gene expression and gene-set enrichment analysis in Caco-2 monolayers during a 30-day timeline with Dexamethasone exposure

2018-06-25

Abstract excerpt

The Caco-2 cell line has served a historically important role as in vitro model for molecular and cellular biology of polarized intestinal epithelia, including for effects of glucocorticoid hormone Dexamethasone. Glucocorticoid hormones modulate the endogenous stress response and are important pharmaceuticals for inflammatory diseases including IBD, yet while they significantly affect immune cells, less is known...

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Literature Corpus work: f43c4f72-c985-531d-bc24-3f1b584dd332
DOI: 10.1101/355552

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