Article

Low-frequency ERK and Akt activity dynamics are predictive of stochastic cell division events

2024-01-20

Abstract excerpt

Understanding the dynamics of intracellular signaling pathways, such as ERK1/2 (ERK) and Akt1/2 (Akt), in the context of cell fate decisions is important for advancing our knowledge of cellular processes and diseases, particularly cancer. While previous studies have established associations between ERK and Akt activities and proliferative cell fate, the heterogeneity of single-cell responses adds complexity to thi...

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Literature Corpus work: f436f36c-c410-5bce-beba-abbe4c9cc138
DOI: 10.1101/2024.01.17.576041

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