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Environmental Xenobiotics and Lysosomal Membrane Permeabilization: Mechanisms of Disruption and Cellular Consequences

2026-04-08

Abstract excerpt

Lysosomes are acidic organelles central to cellular degradation, nutrient sensing, and regulated cell death. The stability of the lysosomal membrane is essential for cell viability, yet it is highly vulnerable to disruption by diverse environmental and endogenous stressors. This review synthesizes current understanding of the molecular mechanisms driving lysosomal membrane permeabilization (LMP) and lysosomal memb...

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Literature Corpus work
f3a6a4a4-6f18-535b-8078-f4be8ea5a8b0
DOI
10.20944/preprints202604.0524.v1
Open publication

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