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Machine learning-guided discovery of a conserved plasmid proteomic signature enables MALDI-TOF MS detection of pOXA-48-carrying <i>Enterobacterales</i>

2026-07-13

Abstract excerpt

OXA-48 carbapenemases are among the most widespread and important resistance mechanisms in Enterobacterales . Yet detecting carbapenemases by conventional workflows necessitates additional testing, thus delaying optimization of therapy and implementation of infection control measures. Here, we present a machine learning approach that identifies the conserved pOXA-48 plasmid directly from routine MALDI-TOF spectra...

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Literature Corpus work
f35fdae7-e8b5-5c2f-859f-d7cc71f70ecb
DOI
10.64898/2026.07.12.738056
Open publication

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Machine learning-guided discovery of a conserved plasmid proteomic signature enables MALDI-TOF MS detection of pOXA-48-carrying <i>Enterobacterales</i>DOI 10.64898/2026.07.12.738056
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