Article

CETP inhibitors and cardiovascular disease: Time to think again

2014-06-10

Abstract excerpt

Inhibition of cholesteryl ester transfer protein (CETP) lowers plasma low-density lipoprotein cholesterol concentration and raises high-density lipoprotein (HDL) cholesterol, suggesting it might prevent cardiovascular disease (CVD). From the outset, however, the concept has been controversial owing to uncertainty about its effects on HDL function and reverse cholesterol transport (RCT). Although there has long bee...

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Literature Corpus work: f33d76a8-0e2e-5eab-b5bb-4a24ea83d4ae
DOI: 10.12688/f1000research.4396.1

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