Article

First Trimester Recurrent Severe Cholestasis and Jaundice: A Case Report on ABCB11 Gene Mutation and hCG-Mediated Pathogenesis with Successful Management

2025-10-19

Abstract excerpt

<title>Abstract</title> <p> <bold>Background</bold> Intrahepatic cholestasis of pregnancy (ICP) typically presents in the second or third trimester with pruritus and elevated serum bile acid levels, resolving postpartum. Early-onset ICP in the first trimester is rare and poses diagnostic and therapeutic challenges. <bold>Case presentation</bold> We report a case of a 25-year-old female patient who presented w...

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Literature Corpus work: f3180f9f-03f3-5e9b-9bee-7ae06b0d38f7
DOI: 10.21203/rs.3.rs-7301463/v1

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