Article

Inhibition of DNA demethylation attenuates experimental necrotizing enterocolitis via suppression of TLR4-mediated inflammation

2026-07-08

Abstract excerpt

<title>Abstract</title> <bold>Background:</bold> Necrotizing enterocolitis (NEC) is a serious inflammatory bowel disease that primarily affects preterm infants. NEC is characterized by damage to the intestinal epithelium, inflammation, and a high mortality rate. Alterations in gene regulation, particularly DNA methylation, have been linked to the development of NEC in preterm infants. However, the significa...

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Literature Corpus work: f30ca0b6-175c-5450-a273-f26d8b05bfa9
DOI: 10.21203/rs.3.rs-10270484/v1

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