Article

The evolutionary dynamics that retain long neutral genomic sequences in face of indel deletion bias: a model and its application to human introns

2022-07-25

Abstract excerpt

Insertions and deletions (indels) of short DNA segments are common evolutionary events. Numerous studies showed that deletions occur more often than insertions in both prokaryotes and eukaryotes. It raises the question why neutral sequences are not eradicated from the genome. We suggest that this is due to a phenomenon we term border-induced selection . Accordingly, a neutral sequence is bordered between conserve...

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Literature Corpus work: f2e9ddfe-99ef-53f0-a7e6-1b1aae373975
DOI: 10.1101/2022.07.25.501396

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