Article

The site of origin of medulloblastoma: Does the neurosurgical perspective support the current concept from molecular data?

2023-03-13

Abstract excerpt

<h4>Purpose: </h4> Developmental gene expression data from medulloblastoma (MB) supported by retrospective MR imaging studies suggest that WNT-MB originate from the region of the embryonic lower rhombic lip (LRL), whereas SHH-MB and non-WNT/non-SHH-activated MB arise from cerebellar precursor matrix regions. This study aims to analyze detailed intraoperative data with regard to the site of origin (STO) and compare...

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Literature Corpus work: f2b07eed-9eab-584b-a739-682bd17c27b6
DOI: 10.21203/rs.3.rs-2658225/v1

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