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Article

Implications of Tumor Location on Subtypes of Medulloblastoma

19 Mar 2013

Abstract excerpt

BACKGROUND: Medulloblastoma (MB) comprises of four molecular subtypes, Sonic hedgehog (SHH), Wingless (WNT), Groups 3 and 4. WNT-subtype MBs were found to arise from midline of the brainstem occupying the fourth ventricle while SHH-subtype occupied the cerebellar hemisphere in a small subset of patients. PROCEDURE: We tested this hypothesis in a large cohort of pediatric MBs comprising of all four molecular...

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PMID: 23512859
DOI: 10.1002/pbc.24511

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