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Perioperative Antibiotic Exposure Duration and Neurocognitive Outcomes in Elderly Surgical Patients: A Prospective Cohort Study of the Gut Microbiota–Brain Axis

2026-06-18

Abstract excerpt

<title>Abstract</title> <p> Background Perioperative neurocognitive dysfunction (PND) affects 10–54% of elderly surgical patients and is associated with prolonged hospitalization and diminished quality of life. The gut microbiota modulates neuroinflammation through the microbiota-gut-brain axis; however, the association between perioperative antibiotic duration and postoperative cognitive outcomes in humans rem...

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Literature Corpus work
f244df5d-99a4-5dbe-8e57-23b534ae615d
DOI
10.21203/rs.3.rs-9678008/v1
Open publication

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Perioperative Antibiotic Exposure Duration and Neurocognitive Outcomes in Elderly Surgical Patients: A Prospective Cohort Study of the Gut Microbiota–Brain AxisDOI 10.21203/rs.3.rs-9678008/v1
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