Article

Modulation of Gut Microbiota and Gut-Brain Axis as a Therapeutic approach in Traumatic brain injury: Implications for Neurological Outcomes

2025-10-17

Abstract excerpt

<h4>Objective</h4> This systematic review aimed to evaluate the impact of gut microbiota modulation including probiotics, dietary interventions, and enteral nutrition strategies on neurological recovery, functional outcomes, morbidity, and mortality in patients with traumatic brain injury (TBI). <h4>Methods</h4> The review was conducted according to PRISMA 2020 guidelines and registered in PROSPERO. A comprehens...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: d2c62416-e96a-500a-981b-27ff57d53c43
DOI: 10.1101/2025.10.15.25338135

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Modulation of Gut Microbiota and Gut-Brain Axis as a Therapeutic approach in Traumatic brain injury: Implications for Neurological OutcomesDOI 10.1101/2025.10.15.25338135Read

An integrated analysis of gut microbiota and the brain transcriptome reveals host-gut microbiota interactions following traumatic brain injurySemantic proximity Read

Altered Fecal Microbiome Years after Traumatic Brain InjurySemantic proximity Read

Unraveling Spinal Cord Injury Nutrition: Effects of Diet on the Host and MicrobiomeSemantic proximity Read

Gut–Brain Axis: Role of Gut Microbiota on Neurological Disorders and How Probiotics/Prebiotics Beneficially Modulate Microbial and Immune Pathways to Improve Brain FunctionsSemantic proximity Read

The altered TBI fecal microbiome is stable and functionally distinctSemantic proximity Read

Traumatic Brain Injury in Mice Induces Acute Bacterial Dysbiosis Within the Fecal MicrobiomeSemantic proximity Read

Gut Microbiota Dysbiosis after Traumatic Brain Injury Contributes to Persistent Microglial Activation Associated with Upregulated Lyz2 and Shifted Tryptophan Metabolic Phenotype.Semantic proximity Read

Gut dysbiosis impairs recovery after spinal cord injury.Semantic proximity Read

Pilot study of the association between microbiome and the development of adverse posttraumatic neuropsychiatric sequelae after traumatic stress exposureSemantic proximity Read

A post-injury immune challenge with lipopolysaccharide following adult traumatic brain injury alters neuroinflammation and the gut microbiome acutely, but has little effect on chronic outcomesSemantic proximity Read

Temporal changes of the oral and fecal microbiota after mild traumatic brain injury in rats by 16s rRNA sequencingSemantic proximity Read

Association between microbiome and the development of adverse posttraumatic neuropsychiatric sequelae after traumatic stress exposureSemantic proximity Read