Article

Germline Contamination and Leakage in Whole Genome Somatic Single Nucleotide Variant Detection

2017-10-17

Abstract excerpt

<h4>Background</h4> The clinical sequencing of cancer genomes to personalize therapy is becoming routine across the world. However, concerns over patient re-identification from these data lead to questions about how tightly access should be controlled. It is not thought to be possible to re-identify patients from somatic variant data. However, somatic variant detection pipelines can mistakenly identify germline v...

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Literature Corpus work: f22d08cc-64ee-503e-9619-ad914fbe0798
DOI: 10.1101/204370

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