Article

Characterization of a Novel Mutation V136L in Bone Morphogenetic Protein 15 Identified in a Woman Affected by POI.

2021-03-19

Abstract excerpt

<title>Abstract</title> <p><bold>Background:</bold> Premature ovarian insufficiency (POI) is an ovarian defect characterized by primary or secondary amenorrhea, hypergonadotropism and hypoestrogenism which occurs before the age of 40 years with a major genetic component. In this study we performed clinical evaluation and genetic analysis of a group of 18 patients with POI.The study involved 18 consecutive women w...

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Literature Corpus work: f18835ba-c74b-54f1-b222-26b7791bbde6
DOI: 10.21203/rs.3.rs-309771/v1

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