Article

The effect of anti-thrombotic therapy on cell-free DNA release from first- and third-trimester placental explants: insights into the mechanism of non-invasive prenatal test (NIPT) failures

2024-05-15

Abstract excerpt

<title>Abstract</title> <p><bold>Objective</bold>: Low molecular weight heparins, including enoxaparin, have been associated with increased non-invasive prenatal testing (NIPT) failures due to low fetal fraction of cell-free (cf) DNA. This study investigated the effect of enoxaparin and antiplatelet therapies on placental tissue in vitro, aiming to determine effects on cfDNA release. <bold>Method</bold>: First- a...

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Literature Corpus work: f176fb91-0d65-5c8f-89d4-f7c5c1040020
DOI: 10.21203/rs.3.rs-4296517/v1

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