Article

Novel RIPK1 Mutations Causing Infantile-onset IBD with Inflammatory and Fistulizing Features

2022-02-24

Abstract excerpt

<title>Abstract</title> <p><bold>Purpose: </bold>Receptor-interacting serine/threonine-protein kinase 1 <italic>(RIPK1</italic>) is an important regulator of necroptosis and inflammatory responses. We present the clinical features, genetic analysis and immune work-up of two patients with infantile-onset inflammatory bowel disease (IBD) resulting from novel <italic>RIPK1 </italic>mutations.<bold>Methods: </bold>Wh...

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Literature Corpus work: f164f6b0-d388-564e-a22d-6b3842762e5a
DOI: 10.21203/rs.3.rs-1347173/v1

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