Article

Very-early-onset inflammatory bowel disease with a partial RIPK1/ BPHL deletion in an infant

2023-03-08

Abstract excerpt

<title>Abstract</title> <p>The monogenic causes of very early-onset inflammatory bowel disease (VEO-IBD) have been defined by advanced genetic studies, which were usually related to primary immunodeficiencies. Receptor-interacting serine/threonine-protein kinase-1 <italic>RIPK-1</italic> protein is an important signalling molecule in inflammation and cell death pathways. Its deficiency may lead to different clini...

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Literature Corpus work: 0b7cd1f0-0e9b-5595-bc1c-150cd948d109
DOI: 10.21203/rs.3.rs-2632287/v1

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