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Integrating computational pathology and multi-transcriptomics to characterize lung adenocarcinoma heterogeneity and prognostic modeling

5 Jun 2025

Abstract excerpt

BACKGROUND: Lung adenocarcinoma (LUAD) is the most prevalent subtype of non-small cell lung cancer (NSCLC), characterized by high molecular and pathological heterogeneity. While traditional histopathology plays a key role in LUAD diagnosis, integrating computational pathology with multi-omics analysis provides novel insights into tumor microenvironment (TME) dynamics and molecular mechanisms. However, the...

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PMID: 40474806
DOI: 10.1097/js9.0000000000002639

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