Article

Alterations of gut microbiota in Down syndrome and their association with Alzheimer’s disease

2026-04-04

Abstract excerpt

<h4>Structured Abstract</h4> <h4>INTRODUCTION</h4> Adults with Down syndrome (DS) have a higher risk of developing Alzheimer’s disease (AD). As gut microbiota (GM) alterations have been reported in AD, we investigated their association with cognitive decline and plasma AD biomarkers in DS. <h4>METHODS</h4> Fecal and plasma samples were collected from 58 adults with DS (21-75 years) and 30 euploid controls (CTRL...

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Literature Corpus work: f107b5cb-1862-522a-9e2b-731018ba1672
DOI: 10.64898/2026.04.03.716276

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