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Gut Microbiome in Down Syndrome

11 Nov 2014

Abstract excerpt

BACKGROUND: Premature aging seriously compromises the health status of Down Syndrome (DS) persons. Since human aging has been associated with a deterioration of the gut microbiota (GM)-host mutualism, here we investigated the composition of GM in DS. METHODS: The observational study presented involved 17 adult DS persons. We characterized the GM structure by 454 pyrosequencing of the V4 region of the 16S rRNA...

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PMID: 25386941
DOI: 10.1371/journal.pone.0112023

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