Article

Improved Method for Predicting GPCR-GPCR Interaction Pairs

2025-08-26

Abstract excerpt

G protein-coupled receptors (GPCRs) can form oligomers, which activate distinct signaling pathways compared to monomeric GPCRs. Oligomerization influences GPCR trafficking, ligand affinity, and signal transduction, and has been implicated in diseases such as schizophrenia and hypertension. Understanding GPCR oligomerization is essential for uncovering disease mechanisms and developing new therapeutic strategies. P...

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Literature Corpus work: f0fc1f0f-75de-584b-a1c6-a3bb917cef66
DOI: 10.22541/au.175622975.51984604/v1

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