Article

Genome-wide identification and comparative analysis of endogenous retroviruses across five breed-representative pig assemblies

2026-07-23

Abstract excerpt

Porcine xenotransplantation offers a promising solution to human organ shortages, yet cross-species transmission of endogenous retroviruses (ERVs) remains a major safety barrier. Current risk assessments predominantly rely on a single reference genome, creating a distinct blind spot regarding ERV diversity and structural variation across diverse genetic backgrounds. We profiled ERV loci across five chromosome-leve...

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Literature Corpus work: f0b6c053-79cd-5dee-b2b7-ea385ac8b643
DOI: 10.1186/s12864-026-13211-x

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