Article

Genome-wide identification and comparative analysis of endogenous retroviruses across five breed-representative pig assemblies

2026-06-24

Abstract excerpt

<title>Abstract</title> <p>Background Porcine xenotransplantation offers a promising solution to human organ shortages, yet cross-species transmission of endogenous retroviruses (ERVs) remains a major safety barrier. Current risk assessments predominantly rely on a single reference genome, creating a distinct blind spot regarding breed-specific ERV diversity and structural variations across diverse genetic backg...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 1239fb18-616a-50f2-afa2-76305509e6ad
DOI: 10.21203/rs.3.rs-9859376/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Genome-wide identification and comparative analysis of endogenous retroviruses across five breed-representative pig assembliesDOI 10.21203/rs.3.rs-9859376/v1Read

Genome-wide identification and comparative analysis of endogenous retroviruses across five breed-representative pig assembliesSemantic proximity Read

Genomic insights into evolutionary journey of the porcine endogenous retrovirusesSemantic proximity Read

Complex evolution of porcine endogenous retrovirusesSemantic proximity Read

The Meishan pig genome reveals structural variation-mediated gene expression and phenotypic divergence underlying Asian pig domestication.Semantic proximity Read

The porcine virome and xenotransplantationSemantic proximity Read

The pig pangenome provides insights into the roles of coding structural variations in genetic diversity and adaptation.Semantic proximity Read

Chromosome-scale <i>de novo</i> assembly and phasing of a Chinese indigenous pig genomeSemantic proximity Read

Beyond the whole genome consensus: unravelling of PRRSV phylogenomics using next generation sequencing technologies.Semantic proximity Read

A Haplotype-resolved Telomere-to-Telomere Pig GenomeSemantic proximity Read

An improved pig reference genome sequence to enable pig genetics and genomics researchSemantic proximity Read

Whole-genome resequencing analyses of five pig breeds, including Korean wild and native, and three European origin breeds.Semantic proximity Read

Structural Variant Detection by Large-scale Sequencing Reveals New Evolutionary Evidence on Breed Divergence between Chinese and European Pigs.Semantic proximity Read