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The pig pangenome provides insights into the roles of coding structural variations in genetic diversity and adaptation.

Genome research - 1 Oct 2023

Li Zhengcao, Liu Xiaohong, Wang Chen, Li Zhenyang, Jiang Bo, Zhang Ruifeng, Tong Lu, Qu Youping, He Sheng, Chen Haifan, Mao Yafei, Li Qingnan, Pook Torsten, Wu Yu, Zan Yanjun, Zhang Hui, Li Lu, Wen Keying, Chen Yaosheng

Abstract excerpt

Structural variations have emerged as an important driving force for genome evolution and phenotypic variation in various organisms, yet their contributions to genetic diversity and adaptation in domesticated animals remain largely unknown. Here we constructed a pangenome based on 250 sequenced individuals from 32 pig breeds in Eurasia and systematically characterized coding sequence presence/absence variations...

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PMID: 37914227
DOI: 10.1101/gr.277638.122
PMCID: PMC10691484

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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