Article

Recent advances in pathophysiology of disseminated intravascular coagulation: the role of circulating histones and neutrophil extracellular traps

2017-12-18

Abstract excerpt

Disseminated intravascular coagulation (DIC) is an acquired condition that develops as a complication of systemic and sustained cell injury in conditions such as sepsis and trauma. It represents major dysregulation and increased thrombin generation in vivo . A poor understanding and recognition of the complex interactions in the coagulation, fibrinolytic, inflammatory, and innate immune pathways have resulted in c...

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Literature Corpus work: f0b5a33b-4dad-52eb-98b3-cbeb85e41591
DOI: 10.12688/f1000research.12498.1

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