Article
Oxytocin receptor gene expression in the basal forebrain in autism: association with receptor binding levels and single nucleotide polymorphisms.
Journal of neurodevelopmental disorders - 19 Feb 2026
Dayley Ethan E, Durham Susan, Palumbo Michelle C, Lundell Jill F, Freeman Sara M
Abstract excerpt
BACKGROUND: The brain’s oxytocin system has been implicated in the neurobiology of autism (ASD), given the role of oxytocin in modulating social function in humans and animals more broadly. Previous work from members of our group reported dysregulation in oxytocin receptor (OXTR) binding in postmortem tissue from the basal forebrain in donors with autism compared to unaffected control donors. This study follows...
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